Enhance MD vs Refills: Pricing, Compounds, and Support Compared
Looking for a straightforward comparison of Enhance MD vs Refills? Quick verdict: Enhance MD undercuts Refills on first-month pricing for semaglutide and tirzepatide, while Refills emphasizes month-to-month flat pricing with free discreet shipping and 24/7 health concierge. This article compares pricing, compound options, flat-rate policies, shipping and patient support, and regulatory notes so you can decide which fits your needs.
See Enhance MD pricing and options
Key difference 1: First-month starting price
Enhance MD lists semaglutide from $49 and tirzepatide from $99 for the first month, explicitly described as introductory prices. Refills lists GLP-1 from $99/month (~$5/day) with semaglutide at $99/mo and tirzepatide at $159/mo. The direct comparison shows Enhance MD offers a lower entry price for semaglutide and the same first-month tirzepatide price as Refills reports only for semaglutide, not for tirzepatide at $159.
Key difference 2: Compounds available on one platform
Both providers offer compounded GLP-1 options. Enhance MD highlights availability of both semaglutide and tirzepatide on one platform and calls out both compounds at specific first-month price points. Refills also offers semaglutide and a GIP+GLP-1 dual agonist option and lists tirzepatide pricing separately. Both emphasize compounded products rather than branded finished products.
Key difference 3: Flat-rate pricing and ongoing cost structure
Enhance MD markets flat-rate pricing with the same price at every dose and no fee escalation during titration, noting the introductory rates apply to first month and that ongoing flat-rate pricing is higher and not always prominently published before intake. Refills also advertises flat pricing, the same price at every dosage, and a month-to-month plan you can cancel anytime with no contracts or cancellation fees. Both providers present flat-rate models; Enhance MD emphasizes flat-rate to avoid dose escalation surprises, while Refills emphasizes simple month-to-month billing and no membership fees.
Key difference 4: Shipping, support, and fulfillment
Refills explicitly includes free discreet shipping, express shipping options, and 24/7 health concierge support, plus shipping and tracking notifications and a monthly refill workflow. Enhance MD materials captured note program details and promotional language but do not supply the same explicit shipping and 24/7 support details in the captured evidence. If shipping speed and ongoing concierge access matter, Refills documents these features directly.
Key difference 5: Regulatory and pharmacy sourcing notes
Both sources state that compounded medications are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality. Refills notes its products come from U.S. pharmacies with boards of pharmacy oversight and third-party USP testing mentioned in captured materials. Enhance MD states its medications are compounded and not FDA-approved and also highlights clinician-directed review before treatment is available.
| Criteria | Enhance MD | Refills |
|---|---|---|
| Starting price | Semaglutide from $49 first month; Tirzepatide from $99 first month | GLP-1 from $99/mo; Semaglutide $99/mo; Tirzepatide $159/mo |
| Flat-rate at every dose | Yes. Same price at every dose; no escalation during titration | Yes. Flat pricing, same price at every dosage |
| Compound options | Semaglutide and tirzepatide available on one platform | Semaglutide, tirzepatide, and a GIP+GLP-1 dual agonist available |
| Shipping and support | Not explicitly detailed in captured evidence | Free discreet shipping; 24/7 health concierge; express shipping |
| Regulatory note | Compounded medications not FDA-approved; clinician review required | Compounded medications not FDA-approved; U.S. pharmacies and third-party testing noted |
How clinician review and access work
Both providers require a licensed clinician to determine appropriateness. Refills describes an intake quiz and clinician review that may lead to a chat or prescription within 24 hours, monthly shipments with refill forms, and clinician consultations at no extra cost. Enhance MD states treatment is available only when a licensed clinician determines it is medically appropriate and promotes clinician-directed care; detailed intake timing and refill workflow were not supplied in the captured evidence.
View Refills monthly plans and shipping
Quick summary and near-conclusion
Enhance MD vs Refills comes down to entry cost versus bundled shipping and concierge support. Enhance MD offers the lowest first-month semaglutide price at $49 and tirzepatide from $99 first month, plus flat-rate dose pricing. Refills starts at $99/mo for GLP-1, includes free discreet shipping and 24/7 health concierge, and highlights month-to-month cancelable plans. Both use compounded products and require clinician review; both state compounded medications are not FDA-approved.
Check Enhance MD clinician-directed options
Start Refills intake quiz and get shipping info
Choose one if…
Choose Enhance MD if you prioritize the lowest first-month semaglutide price (semaglutide from $49 first month) or want both semaglutide and tirzepatide available on a single platform with flat-rate dosing and no escalation during titration.
Choose Refills if you prioritize a clear month-to-month flat price starting at $99/mo, free discreet shipping, 24/7 health concierge access, and a documented refill and shipping workflow in the captured evidence.